8 Great Supplements That Work Best For Joint Health

8 Great Supplements That Work Best For Joint Health

8 Great Supplements That Work Best For Joint Health. As you’ve already witnessed, pain and suffering are brought on by increased joint friction. Supplements are a common alternative to medication, which is often used as the primary treatment for health issues. Even though there are a tonne of supplements out there, we’ll only look at some of the top ones here. These supplements have all been proven to be the most effective for treating joint-related problems by scientific study.

8 Great Supplements That Work Best For Joint Health



  • A complex carbohydrate, glucosamine is largely present in the body in three different forms: glucosamine sulfate, glucosamine hydrochloride, and N-acetylglucosamine.  These are all produced from shellfish, with glucosamine sulfate being the most popular type.
  • This supplement can be taken alone or in conjunction with chondroitin or shark cartilage to treat joint problems and provide additional advantages.
  • This is thought to be advantageous for joint health because it’s crucial for the development of cartilage. As you’ve already observed, cartilage deteriorates and becomes thinner as we age. If anything, supplementation is necessary to maintain it healthy.
  • There is evidence that glucosamine slows this process down. Sulfur is incorporated into the structure to aid in cartilage growth and repair.  Similar to how edema decreases when glucosamine is present.

The benefits of this supplement are sufficient for those with hip or knee arthritis.

  • Glucosamine’s pain-relieving effects only remain for around three months after use, so it may not be a long-term option. Results might not show up for 6 to 8 weeks, but they’ll probably be better than those from utilizing over-the-counter and prescription drugs.
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  • In addition to being found in bone and cartilage naturally, chondroitin is also derived from the cartilage of animals.
  • It is available as chondroitin sulfate and is frequently given along with glucosamine. Its advantages resemble those of glucosamine to some extent. 
  • To minimize excessive rubbing between bones, this supplement aids cartilage in retaining water. Additionally, it slows the development of osteoarthritis.
  • Chondroitin enhances the collagen protein’s capacity to absorb stress when used alone or in combination with other supplements. Additionally, it prevents the activity of enzymes that damage cartilage.
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Hyaluronic acid

  • Hyaluronic acid, a different supplement, is combined with it to create a spring-like molecule. As a result, the cartilage’s flexibility and strength are improved.
  • Chondroitin sulfate also instructs the immune system to increase collagen synthesis to stop cartilage destruction.
  • People with hand arthritis benefit particularly from chondroitin. Even though it doesn’t improve grip strength or lessen the need for painkillers, it nonetheless helps these people with morning stiffness.
  • Since there have been no reports of any negative effects from this supplement, it can also be used as an alternative to NSAIDs for those who cannot take them.
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  • SAM-E is a substance that the body produces naturally. It contributes to the synthesis, activation, and breakdown of several proteins, medicines, and hormones. In order to engage the immune system, the body creates substances that cause inflammatory reactions. SAM-E decreases these mediators’ activity to lessen joint discomfort.
  • Proteoglycan, a component of cartilage, isn’t formed in sufficient quantities in osteoarthritis. In order to stop the breakdown of proteoglycan, SAM-E improves how these enzymes function. Additionally, SAM-E helps to loosen up stiff joints. As a result, mobility is enhanced.
  • It has been observed to be highly beneficial in reversing the extreme tiredness and physical discomfort linked to fibromyalgia.
  • SAM-E can also be used to treat tendonitis, which is an inflammation of tendons in the body. An inflamed bursa is a fluid-filled cushioning sac located between tendons and bones. Joint pain and bursa swelling result from this.
  • SAM-E is especially beneficial for lowering pain and edema. This pill can also help people with chronic lower back pain brought on by obesity or sports injuries.
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  • Chili peppers contain a compound called capsaicin. Because it stings when it makes contact with any body tissue, it is the component that gives you a burning sensation in your mouth. 
  • The way capsaicin works to reduce pain by influencing nerve cells is pretty fascinating. It is applied topically as a cream or patch.
  • It induces the activation of particular nerve receptors that are responsible for the stinging or itching sensation. Long-lasting receptor activation is achieved by capsaicin. 
  • Over-reception eventually causes the receptors’ ability to operate to be lost. As a result, these receptors likewise cease to process pain-inducing impulses.
  • By overusing the receptors, this supplement can help dull pain when taken frequently.
  • Capsaicin is useful in reducing pain brought on by osteoarthritis, fibromyalgia, and rheumatoid arthritis. After just one month of use, its effectiveness is so strong that it can really contribute to a 50% reduction in pain.
  •  Additionally, it aids in easing pain brought on by nerve damage brought on by HIV or diabetic neuropathy.
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  • Turmeric contains a lot of the chemical curcumin. Although turmeric is only used to flavor food or add color to cosmetics, it also has advantages for the health of your joints. Osteoarthritis and rheumatoid arthritis pain are both lessened by curcumin.
  • Curcumin can also help in lowering swelling and inflammation in the area for smooth cushioning and increased mobility when the bursa swells and causes joint pain.
  • It inhibits the enzymes responsible for the body’s production of inflammatory mediators.
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  • The mediator COX-2, which is a target of many painkillers, is one of curcumin’s targets. As a result, curcumin can replace NSAIDs. This pill actually prevents further inflammation, as opposed to treating joint inflammation. This supplement can help those with osteoarthritis of the knee.
  • Curcumin can sometimes be more beneficial than NSAIDS in treating rheumatoid arthritis.
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Omega 3’s

  • Fish oils naturally include omega 3s, which have long been used for their health advantages. Pain alleviation is one of the key advantages of omega 3s.
  • DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) are the two crucial omega 3s for pain relief. The most effective treatment for rheumatoid arthritis discomfort has been omega-3 fatty acids.
  • They don’t repair joint injury or contribute to the production of new cartilage.  Instead, their main purpose is to relieve discomfort.
  • When omega 3s are consumed as supplements, the body transforms them into resolvins. Compared to regular fatty acids, these molecules are 10,000 times more efficient.
  • They prevent the inflammatory immune system mediators from doing their jobs. 
  • The body has its own on-and-off switch for inflammation. Omega 3s prevent the activation of these switches, blocking the progression of the inflammatory pathway.
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Hyaluronic Acid 

  • Synovial fluid, which is present between joints and facilitates easy bone gliding, contains hyaluronic acid. This part begins to disintegrate in rheumatoid arthritis patients, which impairs the fluid’s ability to operate.
  • While its main method of pain relief is through injections, the same substance is also present in supplements in very small doses. Low dosages of this acid have been shown in research to relieve chronic pain and stiffness in joints, though individual responses may vary.
  • Hyaluronic acid 50mg pills can be taken twice a day with meals if you have knee osteoarthritis. Your doctor might suggest an injectable if your condition is more serious. 
  • With less friction between the bones as a result of its incorporation into the synovial fluid, the bones quickly brush against one another. Thus, it improves mobility and lessens joint stiffness.
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  • Collagen is a protein that is the main component of connective tissues such as tendons, ligaments, cartilage, and skin. It is the most abundant protein in the human body and plays a crucial role in providing structure, strength, and elasticity to tissues.
  • Collagen is made up of amino acids, particularly glycine, proline, and hydroxyproline, and it forms a triple helix structure that provides structural support to tissues. In addition to its structural role, collagen also plays a vital role in the regeneration and repair of tissues.
  • Collagen can be found in various food sources such as bone broth, fish, and meat, and it is also available in supplement form.
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  • Due to the importance of joints in these areas—the knee, hip, and ankle—hyaluronic acid is particularly used to treat arthritis in these areas. Arthritis frequently affects the hip’s ball and socket joint, which provides the greatest degree of motion.
  • Therefore, this supplement aids in the rebuilding of the fluid that works as a shock absorber in joints and as grease in bones.
  • When NSAIDs and anti-inflammatory medications are no longer able to relieve a patient’s knee arthritis discomfort, hyaluronic acid injections are recommended.

Alternative Remedies For Joint Pain

You can seek assistance from additional choices when your joint pain becomes more troublesome, such as the following:


  • The most popular drugs for joint pain are analgesics or painkillers. Acetaminophen is a prominent ingredient of Tylenol, a popular medicine.
  • Many recommendations state that this medication is the first line of treatment for knee or hip pain brought on by osteoarthritis.

Side effects from prolonged Tylenol use are the only problem.

  • Gastrointestinal bleeding, ulcers, and kidney function loss are some of this medication’s side effects. It is advised to reduce the dosage or shorten the duration of the treatment.
  • The recommended dose of paracetamol for those who already have conditions like high blood pressure, diabetes, or cardiovascular illnesses is not known.
  • They can still utilize the medication for therapy; they only need to talk to their doctors to determine the dosage.
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  • NSAIDs, commonly known as non-steroidal anti-inflammatory medicines, are also used to treat arthritis pain. Aspirin and ibuprofen are a couple of examples of these medications. The issue, however, is that NSAIDs are more likely to cause adverse effects than paracetamol. NSAIDs can impair the cardiovascular system and kidneys in addition to other organs.
  • Diacerein is a medication that slows down cartilage degeneration by acting extremely slowly. Osteoarthritis patients are given this medication by their doctors. Despite being more effective than a placebo, the medication also raises the risk of diarrhea.
  •  Patients with osteoarthritis are given the antidepressant duloxetine. It is believed to relieve persistent joint discomfort. Additionally, it can cause adverse effects like diarrhea, dry mouth, exhaustion, and sweating.
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Applied Agents

Gels, patches, and liquids are examples of topical treatments for reducing joint discomfort. Depending on how intense the pain is, topical medications can range from mild to strong.  These, however, are not distributed without a prescription.

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Topical medications have been found to have the same pain-relieving properties as NSAIDs, but they come with more advantages than disadvantages. Although not everyone can use these medications, those who prefer to forego oral therapies can benefit from them.

Patients with osteoarthritis can be treated with diclofenac sodium 1% topical gel. For arthritis in the hands, wrists, and elbows, use this gel.

  • Four times a day, the patient must apply 2 grams of the gel to the area that is infected. However, 4 grams of the gel must be used in order to treat arthritis in the knee or ankle. 
  • No matter where you use it, you shouldn’t use more than 32 grams each day. A dosing card is included when you purchase the gel so you can calculate the appropriate dosage for daily use.
  • For pain management, a diclofenac polyamine 1.3% patch is also offered.
  • Simply apply the patch twice daily to the sore joint. Topical medications can also be used topically as drops, such as liquid diclofenac sodium 2%. As it works best for knee arthritis, you must apply 40 drops on each knee four times a day.
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Ibuprofen is a propionic acid derivative with anti-inflammatory, analgesic, and antipyretic properties. It has fewer side effects than other non-selective NSAIDs but its anti-inflammatory properties are weaker. It is unsuitable for conditions where inflammation is prominent, such as acute gout. Dexibuprofen is the active enantiomer of ibuprofen. Naproxen is one of the first choices because it combines good efficacy with a low incidence of side effects (but more than ibuprofen). Fenoprofen is as effective as naproxen, and flurbiprofen may be slightly more effective. Both are associated with slightly more gastrointestinal side effects than ibuprofen.

NSAIDs like ibuprofen can also be turned into topical solutions in addition to these topical treatments. 

  • Such medications are available at compounding pharmacies, although they cost more than regular NSAIDs. Joints that are closest to the surface benefit most from topical treatments. As a result, they will aid in reducing pain from arthritis in the hands, elbows, and ankles.
  • Topical drugs can be used in place of oral medications by those who are diabetic or have heart issues. Additionally, those who have a history of stomach issues or ulcers should choose topical medications over oral NSAIDs.
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  • In between surgery and oral medication, injections fall. Injections are your solution if oral NSAIDs are ineffective for you and you’re not yet prepared for surgery.
  • To enhance the natural hyaluronic acid found in the joints, hyaluronic acid injections are administered for knee arthritis.
  • Injected into a joint, it aids in easing discomfort and swelling. Three to five times per week, these injections are administered. In order to make room for hyaluronic acid, the doctor would first place an empty syringe into the knee. A supplement containing hyaluronic acid is then injected into the empty space.
  • Injections of corticosteroids are also used to treat pain and inflammation. These direct injections are particularly effective for osteoarthritis of the knee. These injections’ positive effects may last a few weeks or even six months.
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  • There are hazards involved with these injections even if they don’t have as many adverse effects as oral drugs. The amount of injections you receive is typically limited by your doctor because frequent usage of these injections might actually hasten cartilage deterioration.
  • Arthrocentesis is a procedure in which the joint fluid is drawn out using a hollow needle. This fluid is frequently removed in order to evaluate it in labs, but when extra fluid is taken out, pain and inflammation are also sufficiently decreased.
  • In some cases, doctors will administer corticosteroid injections in the same joint fluid removal site.
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Physical Exercise

  • The stiffness that comes along with joint discomfort can be greatly reduced with physical therapy. Patients can learn how to move their painful joints with the help of occupational therapists. They also assist patients in remodeling their homes to better suit their needs. 
  • On joints, physical treatment reduces tension. Splints or other aids may also be recommended occasionally to assist the patient with activities of daily living including dressing and driving. 
  • Physical therapy works to make sure you can carry out daily tasks without any trouble. Your therapist would make an effort to broaden your range of motion and develop your surrounding-joint muscles’ strength. This improves mobility and flexibility.
  • Your physical therapist will show you how to perform everyday tasks with the least amount of strain on your joints and stiffness. Since each patient is unique, a therapist would create an exercise program just for you.
  • It will show you how to utilize canes and other assistance equipment while maintaining good posture.
  • A physical therapist would also recommend some ergonomic improvements for your home and instruct you on how to employ a heat or cold therapy method effectively. For instance, a therapist can advise you to purchase customized seats or utilize padded mats.
  • You’ll be able to take morning walks, reach your kitchen cabinets, and bend down to tie your shoes after frequent sessions with a physical therapist.
  • If you continuously perform the exercises, your body will become skilled at the regimen and stronger over time. You can find a therapist in your region who specializes in treating arthritis patients or ask your doctor for suggestions on one.

To achieve the best outcomes, keep in mind that you must combine the therapy approaches rather than depending solely on one.


  • While nutrition and exercise continue to be the cornerstones of excellent joint health, you can also improve your joint health by including things like vitamins and physical or aquatic therapy. 
  • While nutrition and exercise continue to be the cornerstones of excellent joint health, you can also improve your joint health by including things like vitamins and physical or aquatic therapy. 
  • It can be far simpler to prevent joint pain than to deal with the discomfort of joint inflammation and disease susceptibility. 
  • Let your joints appreciate your attention to their needs!